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Capturing the Heterogeneity of the PDAC Tumor Microenvironment: Novel Triple Co-Culture Spheroids for Drug Screening and Angiogenic Evaluation

Mar 25, 2025 | Network Formation Assay, Publications

This study explores the complexity of pancreatic ductal adenocarcinoma (PDAC) and its tumor microenvironment (TME), which plays a crucial role in treatment resistance. To better replicate this environment, the researchers developed triple co-culture spheroid models...

Bridging imaging-based in vitro methods from biomedical research to regulatory toxicology

Feb 18, 2025 | IKOSA AI, Publications

This article published in the Archives of Toxicology, addresses the integration of advanced imaging techniques into regulatory toxicology frameworks. It highlights the increasing use of imaging technologies in biomedical research and experimental toxicology to obtain...

AI Image Analysis and Other Emergent Technologies to Support Adipose Tissue Studies

Feb 3, 2025 | IKOSA AI, Publications

The study highlights the growing interest in adipose tissue as an endocrine organ and its role in conditions like obesity, diabetes, cardiovascular disease, and cancer. Advanced technologies such as 3D cell cultures and Organ-on-a-Chip models are improving in vitro...

Analysis of Osteosarcoma Cell Lines and Patient Tissue Using a 3D In Vivo Tumor Model—Possible Effects of Punicalagin

Mar 4, 2024 | CAM, Publications

In this study, researchers investigated the potential of punicalagin as a supplementary treatment for osteosarcomas, the most prevalent primary malignant bone tumors affecting children, adolescents, and young adults. Despite current therapies like surgery and...

AI-Enhanced Blood Cell Recognition and Analysis: Advancing Traditional Microscopy with the Web-Based Platform IKOSA

Jan 25, 2024 | IKOSA AI, Publications

Traditional pathology utilizes stained blood smears viewed through microscopy, a technique still prevalent despite technological advancements. Typically, manual human assessment accompanies automated methods, maintaining simplicity but lacking comprehensive cell...
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