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Capturing the Heterogeneity of the PDAC Tumor Microenvironment: Novel Triple Co-Culture Spheroids for Drug Screening and Angiogenic Evaluation

Mar 25, 2025 | Network Formation Assay, Publications

This study explores the complexity of pancreatic ductal adenocarcinoma (PDAC) and its tumor microenvironment (TME), which plays a crucial role in treatment resistance. To better replicate this environment, the researchers developed triple co-culture spheroid models...

Bridging imaging-based in vitro methods from biomedical research to regulatory toxicology

Feb 18, 2025 | IKOSA AI, Publications

This article published in the Archives of Toxicology, addresses the integration of advanced imaging techniques into regulatory toxicology frameworks. It highlights the increasing use of imaging technologies in biomedical research and experimental toxicology to obtain...

AI Image Analysis and Other Emergent Technologies to Support Adipose Tissue Studies

Feb 3, 2025 | IKOSA AI, Publications

The study highlights the growing interest in adipose tissue as an endocrine organ and its role in conditions like obesity, diabetes, cardiovascular disease, and cancer. Advanced technologies such as 3D cell cultures and Organ-on-a-Chip models are improving in vitro...

Glycosaminoglycans Modulate the Angiogenic Ability of Type I Collagen-Based Scaffolds by Acting on Vascular Network Remodeling and Maturation

Jan 31, 2025 | CAM, Publications

The study explores how glycosaminoglycans (GAGs) influence the angiogenic properties of type I collagen-based scaffolds.  Researchers incorporated GAGs into collagen scaffolds and used the IKOSA CAM Assay and Network Formation Assay to evaluate vascular network...

Artificial Intelligence (AI) Based Analysis of In Vivo Polymers and Collagen Scaffolds Inducing Vascularization

Jan 29, 2025 | CAM, Publications

The study evaluates the vascularization potential of two collagen-based scaffolds (2D and 3D structures) and a non-collagen scaffold implanted on the chick embryo chorioallantoic membrane (CAM). The researchers utilized classical stereomicroscopic imaging enhanced...

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